COMPOSITION

Each g contains:

Ivermectin 18.7 mg

Praziquantel 140.3 mg

INDICATIONS

lvercure-P Paste is indicated for the treatment and control of the following parasites:

Tapeworms - Anoplocephala perfoliata

Large Strongyles (adults) - Strongy/us vu/garis (also early fonns in blood vessels), S. edentatus (also tissue stages), S. equinus, Triodontophorus spp.

Small Strongyles (adults, including those resistant to some benzimidazole class compounds) - Cyathostomum spp., Cylicocyclus spp., Cyticostephanus spp., Cyticodontophorus spp.

Small Strongyles (fourth-stage larvae)

Pinworms (adults and fourth-stage larvae) - Oxyuris equi

Aicarids (adults and third- and fourth-stage larvae) - Parascaris equorum

Hairworms (adults)

Trichostrongylus axei

Large-mouth Stomach Worms (adults) Habronema muscae

Bois (oral and gastric stages)

Gasterophilus spp.

Lungworms (adults and fourth-stage larvae) Dictyocau/us amfieldi

Intestinal Threadworms (adults)

Strongyloides westeri

Summer Sores caused by Habronema and Draschia spp. cutaneous third-stage larvae

Dermatitis caused by Neck Threadworm microfilariae, Onchocerca sp.

DOSAGE AND ADMINISTRATION

This syringe contains sufficient paste to treat one 1320-lb horse at the recommended dose rate of 91 mcg ivermectin per lb (200 mcg/kg) and 0.68 mg praziquantel per lb (1.5 mg/kg) of body weight. Each weight marking on the syringe plunger delivers enough paste to treat 220lb (100kg) of body weight.

1. While holding plunger, turn the knurled ring on the plunger 1/4 turn to the left and slide it so the side nearest the barrel is at the prescribed weight marking.

2. Lock the ring in place by making a 1 /4 turn to the right.

3. Make sure that the horse's mouth contains no feed.

4. Remove the cover from the tip of the syringe.

5. Insert the syringe tip into the horse's mouth at the space between the teeth.

6. Depress the plunger as far as it will go, depositing paste on the back of the tongue.

7. Immediately raise the horse's head for a few seconds after dosing.

Parasite Control Program

All horses should be included in a regular parasite control program with particular attention being paid to mares, foals, and yearlings. Foals should be treated initially at 4 weeks of age, and routine treatment repeated as appropriate. Consult your veterinarian for a control program to meet your specific needs. lvercure-P Paste effectively controls gastrointestinal nematodes, cestodes and bots of horses. Regular treatment will reduce the chances of colic caused by Anop/ocephala perfoliata and verminous arteritis caused by Strongy!us vulgaris.

Product Advantages

Broad-spectrum Control

lvercure-P Paste kills important internal parasites, including tapeworms, bots and the arterial stages of S. vu/garis, with a single dose. lvercure-P Paste contains two potent antiparasitic agents that are neither benzimidazoles nor organophosphates.

SAFETY

lvercure-P Paste may be used in horses 4 weeks of age and older. Stallions and breeding, pregnant or lactating mares may be treated without adverse effects on fertility.

In a tolerance study in which 3- to 4-week-old foals were treated at 10X once, loose watery stools were observed on post-treatment days 1, 2, and 5-9 in one foal. These signs resolved without treatment by day 10, and no other foals were affected.

In a reproductive safety study, eleven mares were treated with a 3X dose of lvercure-P Paste every two weeks throughout breeding, pregnancy and lactation, up until the foal was three months of age. Ten mares served as controls and were treated with the vehicle paste in a similar manner. An increased incidence of colic was observed in treated mares as compared to control mares. In addition, elevations of GGT and AST were more frequent in the 3X treated mares, and in two mares these enzymes were elevated at the time of colic episodes.

One treated mare was dropped from the study because she did not conceive after three breeding attempts.

Two treated mares had abnormally short diestrous periods of two days and eight days on the first estrous cycle following the birth of the study foal. In addition, one of these two mares failed to ovulate in the second and third estrous cycles.

In the first few weeks of life, foals born to the 3X treated mares had a higher incidence of transient ocular discharge and gastrointestinal disturbances (loose stools, diarrhea) and depression requiring medical intervention as compared to foals born to control mares.

PRECAUTIONS

lvercure-P Paste has been fonnulated specifically for use in horses and ponies only. This product should not be used in other animal species as severe adverse reactions, including fatalities in dogs, may result.

WARNING

Do not use in horses intended for human consumption.

HUMAN WARNINGS

Not for use in humans. Keep this and all drugs out of the reach of children. Refrain from eating or smoking when handling. Wash hands after use. Avoid contact with eyes.

ENVIRONMENTAL WARNINGS

lvermectin and excreted ivermectin residues may adversely affect aquatic organisms. Do not contaminate ground or surface water. Dispose of the syringe in an approved landfill or by incineration.

Store at room temperature (25°C/77°F), with excursions permitted between 15°-30°C

(59°--86°F).

NOTE TO USER

Swelling and itching reactions after treatment with ivermectin paste have occurred in horses carrying heavy infections of neck threadworm (Onchocerca sp. microfilariae). These reactions were most likely the result of microfilariae dying in large numbers. Symptomatic treatment may be advisable. Consult your veterinarian should any such reactions occur. Healing of summer sores involving extensive tissue changes may require other appropriate therapy in conjunction with treatment with lvercure-P Paste. Reinfection, and measures for its prevention, should also be considered. Consult your veterinarian if the condition does not improve.

To report adverse reactions, contact Email: info@jominanimalhealth.com

EQUINE PRODUCTS

WORMERS

Aegis Oral Paste

Pyro-Pam Paste

Ivercure-P Paste

ANTI-INFLAMMATORIES & PAIN RELIEFS

Bute-Zone Powder

ANTI-ULCER

Egus Guard Paste

ANTI-BACTERIALS

Tri-Sul Powder

Tri-Sul Plus Oral Paste

HOOF DISINFECTANT

Sureshot - EQ

SHAMPOO

Glow On

Dermella

Clear Crest

Bloom Wish